Influence of semisynthetic modification of the scaffold of a contact domain of HbS on polymerization: role of flexible surface topology in polymerization inhibition

S Sonati, S Bhutoria, M Prabhakaran… - Journal of Biomolecular …, 2018 - Taylor & Francis
… We reasoned that if this internal deletion is introduced into HbS, the new semisynthetic HbS
… of an important contact domain in inhibiting the Val-6(β)-dependent polymerization. The …

Water, ions, and hemoglobin: effects on allostery and polymerization

MA Rotter, J Jiang, SM Ferrone… - The Journal of Physical …, 2018 - ACS Publications
… of clusters onto existing polymers and thereby growing new … Next, we turn to HbS
polymerization, the consequence of a … We have determined this by analyzing published data on …